Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
713A, a New Metabolite Isolated from a Fungal Strain 713
Ying-shu ZouKe WangYang ZhangYuan LiJie MengJian-bo Wu
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2008 Volume 56 Issue 8 Pages 1189-1190

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Abstract
A new compound named 713A was isolated from the fermentation broth of a fungal strain 713. The structure of 713A was elucidated by spectroscopic methods. In the screening for interleukin-6 (IL-6) receptor antagonist, 713A exhibited inhibitory activity to the binding of IL-6 and IL-6 receptor with an IC50 value of 8.6 μM.
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© 2008 The Pharmaceutical Society of Japan
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