Cyanopeptoline CB071: A Cyclic Depsipeptide Isolated from the Freshwater Cyanobacterium Aphanocapsa sp.

Hyukjae Choi; Sun Kwan Oh; Wonho Yih; Jungwook Chin; Heonjoong Kang; Jung-Rae Rho

doi:10.1248/cpb.56.1191

Notes

Cyanopeptoline CB071: A Cyclic Depsipeptide Isolated from the Freshwater Cyanobacterium Aphanocapsa sp.

Hyukjae Choi, Sun Kwan Oh, Wonho Yih, Jungwook Chin, Heonjoong Kang, Jung-Rae Rho

Author information

Keywords: cyanopeptolin CB071, Aphanocapsa sp., trypsin inhibitor, 2D NMR

JOURNAL FREE ACCESS

2008 Volume 56 Issue 8 Pages 1191-1193

DOI https://doi.org/10.1248/cpb.56.1191

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Abstract

Cyanopeptolin CB071 (1), a trypsin inhibitor, was isolated from the freshwater cyanobacterium Aphanocapsa sp. Its complete structure was determined by detailed NMR spectroscopy and MS analyses, along with chemical reactions. The compound showed inhibition of trypsin at a concentration of IC₅₀=2.5 μM.

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