Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Steroidal Glycosides from Furcraea foetida and Their Cytotoxic Activity
Akihito YokosukaTomoe SanoKen HashimotoHiroshi SakagamiYoshihiro Mimaki
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2009 Volume 57 Issue 10 Pages 1161-1166

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Abstract
Two new spirostanol glycosides (1, 2) and a new furostanol glycoside (3), together with nine known steroidal glycosides (4—12) were isolated from the leaves of Furcraea foetida (Agavaceae). The structures of the new compounds were determined by spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds were evaluated for their cytotoxic activities against HL-60 human leukemia cells, A549 human lung adenocarcinoma cells, HSC-2 human oral squamous carcinoma cells, and HSC-4 human oral squamous carcinoma cells.
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© 2009 The Pharmaceutical Society of Japan
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