Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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One-Step Transformation of Tetrahydropyranyl Ethers Using Indium(III) Triflate as the Catalyst
Tomoko MinenoNana NikaidoHisao Kansui
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2009 Volume 57 Issue 10 Pages 1167-1170

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Abstract
A convergent one-step transformation of tetrahydropyranyl (THP) ethers is described. According to our earlier experiments, indium(III) triflate has proven to be an efficient catalyst for the transformation of THP ethers into their corresponding acetates. In further intensive work, we have developed a useful transforming reaction of THP ethers using various anhydride moieties. Indium(III) triflate was confirmed as a suitable catalyst, furnishing good to excellent yields. The details of this one-step transformation are described.
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© 2009 The Pharmaceutical Society of Japan
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