New C₁₉- and C₁₈-Diterpenoid Alkaloids from Delphinium anthriscifolium var. savatieri

Abstract

Three new C₁₉-diterpenoid alkaloids, anthriscifoldines A—C (1—3), and two new C₁₈-diterpenoid alkaloids, anthriscifolcines F and G (5, 6), were obtained from the whole herbs of Delphinium anthriscifolium var. savatieri during our further investigation on a larger scale of recollected plants. Their structures were elucidated based on the interpretation of NMR and high-resolution ESI-MS data, and chemical transformation. In addition, five known C₁₉-diterpenoid alkaloids were also isolated and identified as nudicaulamine (4), delbruninol (7), blacknine (8), winkleriline (9), and deltaline (10).