Novel Norhumulene and Xeniaphyllane-Derived Terpenoids from a Formosan Soft Coral Sinularia gibberosa

Shin-Pin Chen; Jui-Hsin Su; Hsiao-Chien Yeh; Atallah Fouad Ahmed; Chang-Feng Dai; Yang-Chang Wu; Jyh-Horng Sheu

doi:10.1248/cpb.57.162

Regular Articles

Novel Norhumulene and Xeniaphyllane-Derived Terpenoids from a Formosan Soft Coral Sinularia gibberosa

Shin-Pin Chen, Jui-Hsin Su, Hsiao-Chien Yeh, Atallah Fouad Ahmed, Chang-Feng Dai, Yang-Chang Wu, Jyh-Horng Sheu

著者情報

キーワード: diterpenoid, xeniaphyllane, Sinularia gibberosa, cytotoxic

ジャーナルフリー

2009 年 57 巻 2 号 p. 162-166

DOI https://doi.org/10.1248/cpb.57.162

詳細

抄録

A novel skeletal norhumulene (1) and six xeniaphyllane-derived compounds, including norditerpenoids (2, 3) and diterpenoids (4—7), were isolated from the EtOAc extract of the Formosan soft coral Sinularia gibberosa. Their structures were elucidated by spectroscopic analysis. In vitro cytotoxic evaluation of the above metabolites revealed that 2 and 4 showed weak cytotoxicity toward a few cancer cell lines.

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