Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Three New Bibenzyl Derivatives from Dendrobium candidum
Yan LiChun-Lan WangYa-Jun WangShun-Xing GuoJun-Shan YangXiao-Mei ChenPei-Gen Xiao
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2009 年 57 巻 2 号 p. 218-219

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Three new compounds were isolated from the stems of Dendrobium candidum: (S)-3,4,4′-trihydroxy-5,α-dimethoxybibenzyl (1), named dendrocandin C; (S)-3,4,4′-trihydroxy-5-methoxy-α-ethoxybibenzyl (2), named dendrocandin D; and 3,3′,4,4′-tetrahydroxy-5-methoxybibenzyl (3), named dendrocandin E. Their structures were elucidated by 1D- and 2D-NMR spectroscopy and mass spectroscopy. The isolated compounds exhibited potent antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging test, with IC50 values of 34.2, 34.5, and 15.6 μM for compounds 1, 2, and 3, respectively. Vitamin C was used as positive control with IC50 23.2 μM.
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© 2009 The Pharmaceutical Society of Japan
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