Delaumonones A and B, New Antiplasmodial Quassinoids from Laumoniera bruceadelpha

Shiori Oshimi; Aki Takasaki; Yusuke Hirasawa; Takahiro Hosoya; Khalijah Awang; A. Hamid A. Hadi; Wiwied Ekasari; Aty Widyawaruyanti; Hiroshi Morita

doi:10.1248/cpb.57.867

Notes

Delaumonones A and B, New Antiplasmodial Quassinoids from Laumoniera bruceadelpha

Shiori Oshimi, Aki Takasaki, Yusuke Hirasawa, Takahiro Hosoya, Khalijah Awang, A. Hamid A. Hadi, Wiwied Ekasari, Aty Widyawaruyanti, Hiroshi Morita

Author information

Keywords: quassinoid, delaumonone, antimalarial activity, Laumoniera bruceadelpha

JOURNAL FREE ACCESS

2009 Volume 57 Issue 8 Pages 867-869

DOI https://doi.org/10.1248/cpb.57.867

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Abstract

New quassinoids, delaumonones A (1) and B (2) have been isolated from the bark of Laumoniera bruceadelpha NOOTEBOOM (Simaroubaceae) and the structures were elucidated by 2D NMR analysis and a chemical correlation. Delaumonones showed an antimalarial activity against Plasmodium falciparum.

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