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Chemical and Pharmaceutical Bulletin
Vol. 58 (2010) No. 1 P 30-33



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Six new sesquiterpenoids, paralemnolins J—O (1—6), along with one novel norsesquiterpenoid, paralemnolin P (7), have been isolated from the soft coral Paralemnalia thyrsoides. The structures of metabolites 1—7 were established on the basis of extensive NMR study and chemical methods. The structure of 5 was further confirmed by a single-crystal X-ray analysis. Cytotoxicity of these metabolites toward a limited panel of cancer cell lines also is described.

Copyright © 2010 The Pharmaceutical Society of Japan

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