Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Synthesis and Properties of Diazirinyl Organo-Platinum Compounds for Manipulations of Photoaffinity Labeled Components
Makoto Hashimoto, Keitaro Furukawa, Takenori Tomohiro, Yasumaru Hatanaka
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Keywords: photoaffinity labeling, diazirine, organo-platinum compound
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2010 Volume 58 Issue 3 Pages 405-407

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Abstract
Synthesis of diazirinyl organo-platinum complexes, which specifically interact with purine base, characterization of photoreactivity and interaction between guanosine 5′-monophosphate (GMP) were examined. The results indicated that the diazirinyl organo-platinum complex was useful for manipulations of photoaffinity labeled components.
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© 2010 The Pharmaceutical Society of Japan
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