Neolignans from Schisandra wilsoniana and Their Anti-human Immunodeficiency Virus-1 Activities

Guang-Yu Yang; Rui-Rui Wang; Huai-Xue Mu; Yin-Ke Li; Wei-Lie Xiao; Liu-Meng Yang; Jian-Xin Pu; Yong-Tang Zheng; Han-Dong Sun

doi:10.1248/cpb.59.1344

Regular Articles

Neolignans from Schisandra wilsoniana and Their Anti-human Immunodeficiency Virus-1 Activities

Guang-Yu Yang, Rui-Rui Wang, Huai-Xue Mu, Yin-Ke Li, Wei-Lie Xiao, Liu-Meng Yang, Jian-Xin Pu, Yong-Tang Zheng, Han-Dong Sun

Author information

Guang-Yu Yang
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science
Rui-Rui Wang
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences
Huai-Xue Mu
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
School of Chemistry and Biotechnology, Yunnan Nationalities University
Yin-Ke Li
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
School of Chemistry and Biotechnology, Yunnan Nationalities University
Wei-Lie Xiao
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
Liu-Meng Yang
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences
Jian-Xin Pu
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
Yong-Tang Zheng
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences
Han-Dong Sun
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences

Keywords: Schisandra wilsoniana, neolignan, marphenol G, anti-human immunodeficiency virus-1 activity

JOURNAL FREE ACCESS

2011 Volume 59 Issue 11 Pages 1344-1347

DOI https://doi.org/10.1248/cpb.59.1344

Details

Abstract

Four new neolignans, marphenols G—J (1—4), together with two known ones, were isolated from the leaves and stems of Schisandra wilsoniana. The structures of 1—4 were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. New compounds 1—4 were tested for their anti-human immunodeficiency virus (HIV)-1 activities and they showed weak bioactivities.

Corresponding author

Register with J-STAGE for free!