Medicinal Flowers. XXXII. Structures of Oleanane-Type Triterpene Saponins, Perennisosides VIII, IX, X, XI, and XII, from the Flowers of <i>Bellis perennis</i>

Toshio Morikawa; Xuezheng Li; Eriko Nishida; Seikou Nakamura; Kiyofumi Ninomiya; Hisashi Matsuda; Makoto Hamao; Osamu Muraoka; Takao Hayakawa; Masayuki Yoshikawa

doi:10.1248/cpb.59.889

Notes

Medicinal Flowers. XXXII.

Structures of Oleanane-Type Triterpene Saponins, Perennisosides VIII, IX, X, XI, and XII, from the Flowers of Bellis perennis

Toshio Morikawa, Xuezheng Li, Eriko Nishida, Seikou Nakamura, Kiyofumi Ninomiya, Hisashi Matsuda, Makoto Hamao, Osamu Muraoka, Takao Hayakawa, Masayuki Yoshikawa

Author information

Keywords: Bellis perennis, Asteraceae, triterpene saponin, perennisoside, Daisy flower

JOURNAL FREE ACCESS

2011 Volume 59 Issue 7 Pages 889-895

DOI https://doi.org/10.1248/cpb.59.889

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Abstract

Five new triterpene saponins perennisosides VIII (1), IX (2), X (3), XI (4), and XII (5) were isolated from the MeOH-eluated fraction of the methanolic extract from the flowers of Bellis perennis. The MeOH-eluted fraction of the methanolic extract from the flowers of B. perennis was found to inhibit gastric emptying in olive oil-loaded mice at a dose of 200 mg/kg, per os (p.o.). The stereostructures of 1—5 were elucidated on the basis of chemical and spectroscopic evidence.

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