A Lanostane Triterpenoid and Three Cholestane Sterols from Tilia kiusiana

Marie Shimada; Masaaki Ozawa; Kojiro Iwamoto; Yoshiyasu Fukuyama; Akio Kishida; Ayumi Ohsaki

doi:10.1248/cpb.c14-00200

Notes

A Lanostane Triterpenoid and Three Cholestane Sterols from Tilia kiusiana

Marie Shimada, Masaaki Ozawa, Kojiro Iwamoto, Yoshiyasu Fukuyama, Akio Kishida, Ayumi Ohsaki

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Keywords: Tilia kiusiana, Tiliaceae, triterpene, sterol, cytotoxicity

JOURNAL FREE ACCESS FULL-TEXT HTML

2014 Volume 62 Issue 9 Pages 937-941

DOI https://doi.org/10.1248/cpb.c14-00200

J-STAGE : cpb 66 7 pp.771-772

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Abstract

Kiusianins A–D (1–4) were isolated from the leaves of a Japanese endemic plant, Tilia kiusiana, together with 14 known compounds. The structures of a new lanostane-type triterpenoid 1 and three new cholestane-type sterols 2–4 were elucidated by spectroscopic methods, including two dimensional (2D) NMR. All the compounds isolated were evaluated for their cytotoxicity against two human cancer cell lines, HeLa and HL-60.

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