Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Clean Synthesis of N-Pyrrolyl Azoles by Metal-Free Oxidative Cross-Coupling Using Recyclable Hypervalent Iodine Reagent
Koji MorimotoRyosuke OgawaDaichi KosekiYusuke TakahashiToshifumi DohiYasuyuki Kita
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2015 Volume 63 Issue 10 Pages 819-824

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Abstract

The facile and clean oxidative coupling reaction of pyrroles with azoles has been achieved using the recyclable hypervalent iodine(III) reagents having adamantane structures. These iodine(III) reagents could be recovered from the reaction mixtures by a simple solid–liquid separation, i.e., filtration, for reuse.

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© 2015 The Pharmaceutical Society of Japan
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