Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Metabolism of Drugs. XXVI. Metabolic Fate of p-Hydroxybenzoic Acid and its Derivatives in Rabbit. (2).
Hisao TsukamotoSeisuke Terada
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1962 Volume 10 Issue 2 Pages 86-90

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Abstract
The ether-type glucuronide of p-hydroxybenzoic acid was isolated from the urine of rabbits receiving methyl p-hydroxybenzoate and its structure was established as p-carboxyphenyl-β-D-glucopyranosiduronic acid. Three main metabolites, p-hydroxybenzoic acid, p-hydroxyhippuric acid, and the ether-type glucuronide, were identified in the urine, and the ester-type glucuronide and p-carboxyphenyl sulfate were proved as minor metabolites by means of paper chromatography.
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© The Pharmaceutical Society of Japan
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