Studies on Oxidized Starch Sulfates for Medical Purposes. II. Anticoagulant Activity of Sulfates of Oxidized Starch and its Derivatives.
1962 年 10 巻 3 号 p. 167-171
詳細
1962 年 10 巻 3 号 p. 167-171
Anticoagulant activity of synthetic heparinoids was determined and its relationship to the sulfur content and/or to the molecular size (viscosity) was investigated. Carboxyl residue at C-6 in the glucose unit was proved to weaken the toxicity. Heparin, oxidized starch sulfate and sulfate of the reduced product of oxidized starch were compared for their stability against acids and alkalis.
