Abstract
The structures of three metabolites isolated from the urine of rabbits and dogs admintstered with meprobamate (2-methyl-2-n-propyl-1, 3-propanediol dicarbamate) were established as keto-meprobamate [2-methyl-2-(2-oxo-propyl)-1, 3-propanediol dicarbamate], hydroxy-meprobamate [2-methyl-2-(2-hydroxypropyl)-1, 3-propanediol dicarbamate] and carboxy-meprobamate [2-methyl-2-(2-carboxyethyl)-1, 3-propanedioi dicarbamate].