Abstract
5-Aminoimidazole-4-carboxthioamide was synthesized by the phosphorus pentasulfide-pyridine treatment of 5-aminoimidazole-4-carboxamide. The structure was elucidated both by chemical and physical means. 1-β-D-Ribofuranosy1-4-methyl-5-nitroimidazole and 1-β-D-ribofuranosy1-4-nitro-5-methoxycarbonylimidazole were synthesized by the condensation of appropriate imidazole chloro-mercury salt with 2, 3, 5-tri-Obenzoyl-D-ribofuranosyl chloride followed by the removal of protecting groups.
