Studies on Coenzyme Analogs. XII. Synthesis of 5-Dimethylaminouridine-and 3-Methyluridine 5'-Phosphate

Abstract

The reaction of 5-bromo-2', 3'-isopropylideneuridine and dimethylamine gave 5-dimethylamina derivative and this was phaspharylated ta 5-dimethylaminauridine 5'-phosphate by polyphosphoric acid. 3-Methyluridine 5'-phosphate was also synthesized from 3-methyl-2', 3'-isopropylideneuridine by polyphosphoric acid.