Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Acylase Activity and Microörganisms. XVII. Optical Resolution of Tryptophan, 2-Aminohexanedioic Acid, and 2-Aminoöctanoic Acid by Metabolism of Soil Bacteria on Benzoyl Derivatives of DL-Amino Acids
Yukio KamedaKatsuhiko MatsuiYukio KimuraEtsuko ToyouraEiji Takeuchi
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1962 Volume 10 Issue 9 Pages 827-830

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Abstract
The metabolic activities of 3 strains (KT-303, KT-304, and KT-305) of soil bacteria were tested on tryptophan and its benzoyl derivatives (Table I), and it was found that KT-303 and KT-305 metabolized benzoyl-DL-tryptophan to produce L-tryptophan and benzoyl-D-tryptophan respectively.
Two strains (KT-230 and KT-231) of soil bacteria had the activity to metabolize benzoyl derivatives of 2-aminohexanedioic acid and 2-aminooctanoic acids to yield L-2-aminohexanedioic acid, N-benzoyl-D-2-aminohexanedioic acid, L-2-aminooctanoic acid, and N-benzoyl-D-2-aminooctanoic acid respectively.
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© The Pharmaceutical Society of Japan
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