Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Metabolism of Drugs. XXXII. The Metabolic Fate of Secobarbital [5-Allyl-5-(1-methylbutyl) barbituric Acid].
Hisao TsukamotoHidetoshi YoshimuraHiroyuki Ide
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1963 Volume 11 Issue 1 Pages 9-13

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Abstract
The metabolic fate of secobarbital [5-allyl-5-(1-methylbutyl) barbituric acid] in rabbits were studied and two main metabolites were isolated in addition to the unchanged secobarbital. The structure of the metabolites were established as 5-allyl-5-(1-methyl-3-carboxypropyl)-and 5-allyl-5-(1-methyl-3-hydroxybutyl) barbituric acid.
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© The Pharmaceutical Society of Japan
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