Author's Organization：Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University
The metabolic fate of secobarbital [5-allyl-5-(1-methylbutyl) barbituric acid] in rabbits were studied and two main metabolites were isolated in addition to the unchanged secobarbital. The structure of the metabolites were established as 5-allyl-5-(1-methyl-3-carboxypropyl)-and 5-allyl-5-(1-methyl-3-hydroxybutyl) barbituric acid.
