Abstract
The metabolic fate of secobarbital [5-allyl-5-(1-methylbutyl) barbituric acid] in rabbits were studied and two main metabolites were isolated in addition to the unchanged secobarbital. The structure of the metabolites were established as 5-allyl-5-(1-methyl-3-carboxypropyl)-and 5-allyl-5-(1-methyl-3-hydroxybutyl) barbituric acid.