Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Decomposition and Stabilization of Drugs in Solution. XIV. Stabilization of Methantheline Bromide and Choline Derivatives in Aqueous Solution by Surface-active Agents.
野上 寿粟津 荘司岩鶴 素治
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1963 年 11 巻 10 号 p. 1251-1255

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1) The decomposition of methantheline bromide was repressed by the addition of alkyl sulfate (anionic surfactant). The longer the alkyl chain length of alkyl sulfate, the greater the effect was. 2) The addition of surfactant enhanced the stability of cholinesters, and the effect increased with the acyl chain length.

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© The Pharmaceutical Society of Japan
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