Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Nuclear Magnetic Resonance Studies. IV. Solvent Effect of Trifluoroacetic Acid on Proton Resonances.
Yutaka KawazoeMasako Ohnishi
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1963 Volume 11 Issue 2 Pages 243-248

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Abstract
The differences of the chemical shifts measured in two different solvents of carbon tetrachloride and trifluoroacetic acid were determined and tubulated with various kinds of compounds. The solvent effect of trifluoroacetic acid represented by the above chemical shift differences were characteristic for each proton-type. This fact may be applicable to the qualitative analysis of the compounds. It is also tried to correlate this solvent effect with the basicity of the functional group neighboured by the proton concerned.
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© The Pharmaceutical Society of Japan
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