Synthetic Studies on Sorigenins. IV. Synthesis of γ-Lactone of 3-Hydroxymethyl-4-methoxy-2-naphthoic Acid.

Abstract

As exploratory experiments for the synthesis of 3-hydroxymethyl-4, 5, 7-trimethoxy-2-naphthoic acid γ-lactone in the course of synthethic studies on α-sorigenin, the synthesis of 3-hydroxymethyl-4-methoxy-2-naphthoic acid γ-lactone (VI) was accomplished by the two routes shown in Chart 1 and 2.