17β-(2-alkylamino-(or 2-arylamino- or 2-N, N-alkylarylamino-)-4-thiazolyl) androst-4-en-3-one derivatives were prepared from Reichstein's compound S 21-iodide, cortisone 21-iodide and desoxycorticosterone 21-iodide or corresponding 21-mesylate with N-alkylthiourea, N-arylthiourea or N, N-alkylarylthiourea respectively. Some of these compounds were found to have a digitalis-like properties (cardiac glucoside properties) as a result of pharmacological test.
