Abstract
Five NAD analogs have been synthesized in which the adenosine portion of NAD was replaced by deoxyadenosine, guanosine, cytidine, uridine and thymidine, and their comparative coenzymatic activity with that of NAD was investigated with yeast alcohol dehydrogenase, beef liver glucose dehydrogenase and rabbit muscle lactic dehydrogenase. The influence of the analogs on the reaction rate of NAD was also studied.
