Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Potential Anti-cancer Agents. XI. Synthesis of 4- and 5-Azidopyridazine 1-Oxide.
Takanobu ItaiShozo Kamiya
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1963 Volume 11 Issue 8 Pages 1059-1064

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Abstract
Reaction of 3, 4, 5-trichloropyridazine (IV) with sodium methoxide was examined. 4-Azidopyridazine 1-oxide (XVII) and 5-azidopyridazine 1-oxide (XXI) were synthesized from corresponding hydrazino compounds (XIV, XX) with nitrous acid, and XVII was also derived from 4-chloropyridazine 1-oxide (XIII) with sodium azide.
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© The Pharmaceutical Society of Japan
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