Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Synthetic Nucleosides, II. Novel Synthesis of Pyrimidine Glucosides.
Takuzo NishimuraIssei Iwai
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1964 Volume 12 Issue 3 Pages 357-361

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Abstract
A new synthetic method is developed for the synthesis of pyrimidine glucosides by the fusion of trimethylsilylpyrimidines and α-acetobromoglucose followed by mild alkaline treatment. 1-β-D-Glucopyranosyl-uracil, -thymine, and-cytosine (picrate) were obtained in good yields. The physical constants of thus obtained nucleosides and their acetyl derivatives show good agreement with those of reported nucleosides.
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© The Pharmaceutical Society of Japan
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