Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Pattern of Enzyme Activity of the Nitrogen Mustard Sensitive and the Resistant Ascites Tumors.
Hideo SugimotoMichiko Aoshima
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1964 Volume 12 Issue 3 Pages 362-369

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Abstract
The paper deals with a comparison of the pattern of activity of enzymes of the original Yoshida sarcoma with that of a line of the same tumor, which is 10, 000-fold resistant to HN2. Only difference so far obtained by these experiments with sixteen kinds of enzymes was found in the activity of sulfatase. Patterns of enzyme activity of several rat ascites hepatomas were also presented, some of which are inherently resistant to HN2, some are very sensitive, and the rest of them moderately sensitive.
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© The Pharmaceutical Society of Japan
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