Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Metabolism of trans-π-Oxocamphor.
Zenzo TamuraToshio Imanari
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1964 Volume 12 Issue 3 Pages 370-375

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Abstract
The fate of medical dose of subcutaneously administered trans-π-oxocamphor (I) in human body was investigated. trans-π-Apocamphorcarboxylic acid (III) and its ester glucuronide (III-G) were detected as the main urinary metabolites of I, while trans-π-hydroxycamphor glucuronide was detected as a minor one. Determination by gas chromatography demonstrated that more than 80% of administered I was excreted as III and III-G during 8 hours.
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© The Pharmaceutical Society of Japan
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