Abstract
The fate of medical dose of subcutaneously administered trans-π-oxocamphor (I) in human body was investigated. trans-π-Apocamphorcarboxylic acid (III) and its ester glucuronide (III-G) were detected as the main urinary metabolites of I, while trans-π-hydroxycamphor glucuronide was detected as a minor one. Determination by gas chromatography demonstrated that more than 80% of administered I was excreted as III and III-G during 8 hours.