Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Metabolism of Drugs. XLII. Isolation of Ester Glucuronides of p-Aminosalicylic Acid and Salicylic Acid from the Urine of Rabbits.
Hisao TsukamotoKeitaro KatoKazuo Yoshida
Author information
JOURNAL FREE ACCESS

1964 Volume 12 Issue 6 Pages 731-734

Details
Abstract
1. The ester glucuronide of p-aminosalicylic acid was isolated from the urine of rabbits administered with p-aminosalicylic acid. The methyl acetyl derivative of this compound was identified with synthetic methyl (2-acetoxybenzoyl-4-acetamido-2, 3, 4-tri-O-acetyl-β-D-glucopyranosid) uronate. 2. The ester glucuronide of salicylic acid was isolated as methyl (2-acetoxybenzoyl-2, 3, 4-tri-O-acetyl-β-D-glucopyranosid) uronate from the urine of rabbits administered with salicylic acid, and the structure was confirmed with the synthetic compound.
Content from these authors
© The Pharmaceutical Society of Japan
Previous article Next article
feedback
Top