Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
A New Action of Anion Exchange Resins on the Lactone Ring of Some Carbohydrates
Morizo IshidateYuji ImaiYoshinobu HirasakaKenji Umemoto
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1965 Volume 13 Issue 2 Pages 173-176

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Abstract
It was found that some carbohydrates with lactone group was quantitatively absorbed on anion exchange resins in aqueous solution, and by elution with suitably mineral acid they were recovered in high yield as the corresponding free acid. Thus D-glucuronic acid (II), 1, 2-O-isopropylidene-D-glucofuranosiduronic acid (V), methyl D-glucofuranosiduronic acid (VII) and L-gulonic acid (IX) were obtained advantageously from their lactone derivatives. It is noteworthy that some of them have not been obtained in success by the direct neutralization of lactone derivatives with alkaline medium.
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© The Pharmaceutical Society of Japan
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