Studies on the Pyrimidine Derivatives and Related Compounds. XXXIX. On the Oxidation Products of 2-Pheny1-4-(2-methyl-4-amino-5-pyrimidyl)methyl-5-methyl-6-(2-benzoyloxy or hydroxy)-ethyl-4H-1, 4-thiazin-3(2H)-one

Abstract

It has revealed that 2-benzoyl-2-hydroxy-3-(2-methyl-4-amino-5-pyrimidyl)methyl-4-methyl-5-(2-benzoyloxy or hydroxy)-ethylthiazoline (VIII) or (IX) of pseudo-thiamine type was produced from the oxidation reaction of 2-phenyl-4-(2-methyl-4-amino-5-pyrimidyl)methyl-5-methyl-6-(2-benzoyloxy or hydroxy)ethyl-4H-1, 4-thiazin-3(2H)one (III) or (IV). In addition, several reactions of these new compounds have been studied.