Studies on the Syntheses of Heterocyclic Compounds. CXCV. The Structure of a Yellow Substance formed by Mild Oxidation of Aminopyrine.

Abstract

A yellow substance, which slightly formed as a by-product in case of preparation of a molecular compound by fusion of aminopyrine (I) with secobarbital or barbital in the presence of air, was also obtained by mild oxidation of I with air in a poor yield. Structural elucidation by physical and chemical methods was carried out, leading eventually to confirm the formula (II) for the yellow substance as above.