Biochemical Syntheses. II. Microbial Transformation of Cyperotundone to Sugeonol and Isopatchoul-4-en-3-on-8α-ol

Abstract

Cyperotundone (I), a constituent of nutgrass (Cyperus rotundus (Cyperaceae)), has been converted by exposure to Corlicium sasakii into its oxygenated congeners, sugeonol (II), another constituent of nutgrass, and isopatchoul-4-en-3-on-8α-ol (III : R=H)) whose stereostructure has been deduced by its spectral properties.