Author's Organization:/ School of Pharmacy, Kitasato University Institute of Applied Microbiology, University of Tokyo (Present Address):National Institute of Hygienic Sciences, Osaka Branch Institute of Applied Microbiology, University of Tokyo
In the microbial transformation by Trametes sanguinea, 14β-bromocodeinone (IV) was first converted enzymatically into 14β-bromocodeine (VI), which was gradually affected chemically to form VII, II, and VIII as the final products.