Studies on Metabolism of 3-Deoxysteroids. IV. Synthesis of 2, 17-Oxygenated 5-Dehydro- and 5β-Androstanes

Abstract

For the studies on metabolic fate of 3-deoxydehydroepiandrosterone in man, 5-dehydro- and 5β-androstanes having oxygen functions at both C-2 and C-17, the possible metabolites, have been synthesized as shown in Chart 1.