Colorimetric Determination of Pyruvic Acid with p-Dimethylaminobenzaldehyde

Abstract

A new colorimetric method for the determination of pyruvic acid is presented on the basis of a new color reaction of the acid with p-dimethylaminobenzaldehyde in dimethylsulfoxide solution in the presence of strong alkali. The method is selective for pyruvic acid among ketonic acids, but interfered by acetone, acetaldehyde, bilirubin, glucose, D-glucuronolactone and ascorbic acid.