Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Oxidation of 2, 3-Disubstituted Indole Derivatives with Selenium Dioxide
SHIN-ICHIRO SAKAIAKINORI KUBOKIMIO KATSUURAKYOKO MOCHINAGAMAYUMI EZAKI
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1972 Volume 20 Issue 1 Pages 76-81

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Abstract
The action of selenium dioxide on several 2, 3-disubstituted indole derivatives was found to give the corresponding 2-acylindoles as shown in Table I. In the case of tricyclic mides, (VI and VII), this oxidation reaction resulted in the formation of a-vinylindoles and organoselenium compounds. On the basis of these products, the mechanism of the oxidation with selenium dioxide is discussed.
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© The Pharmaceutical Society of Japan
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