Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
The Structure of Aristeromycin
TOYOKAZU KISHIMASAYUKI MUROITAIKI KUSAKAMASAO NISHIKAWAKAZUHIDE KAMIYAKOMEI MIZUNO
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1972 Volume 20 Issue 5 Pages 940-946

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Abstract
Aristeromycin, a new antibiotic isolated from the culture broth of Streptomyces citricolor, exhibits inhibition of the growth of Pyricularia oryzae and Xanthomonas oryzae. The structure of aristeromycin, apart from stereochemistry, was assumed as (A) on the basis of physicochemical and chemical properties of aristeromycin and its pentaacetate. By X-ray analysis of aristeromycin hydrobromide the assumed structure was ascertained and the absolute configuration was established as (1'R, 2'S, 3'R, 4'R)-9-[β-2'α, 3'α-dihydroxy-4'β-(hydroxymethyl) cyclopentyl] adenine.
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© The Pharmaceutical Society of Japan
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