Abstract
The synthesis three stereoisomers of eritadenine (I) ; D-threo-(II), L-threo-(III) and L-eritadenine (IV), described. D-threo-Eritadenine (II) was derived from eritadenine by utilizing a novel ■thro-threo epimerization. L-threo-Eritadenine (II) was synthesized, starting from L-threonolactone dibenzoate (IX), through the route involving an imidazole ring closure. The synthesis of L-eritadenine (IV) was achieved conveniently by direct condensation of adenine and L-erythronolactone acetonide (XX).