Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthetic Studies on Anthracyclinones. XIII. Conversion of Bisanhydro-γ-rhodomycinone into Bisanhydrodaunomycinone
堀井 善一尾崎 〓山村 志郎西角 孝子花岡 美代次百瀬 雄章
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1974 年 22 巻 1 号 p. 93-98

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The synthesis of bisanhydrodaunomycinone (II) was achieved via bisanhydro-γ-rhodomycinone (III) by 7 step procedure envolving the transformation of ethyl side chain in III into acetyl group as shown in Chart 2. The formation of an ana-quinone system on methylation of 6, 11-dihydroxynaphthacenequinones (II and III) was discussed from infrared and ultraviolet spectral comparison.
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© The Pharmaceutical Society of Japan
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