Author's Organization：Faculty of Pharmaceutical Sciences, Osaka University Faculty of Pharmaceutical Sciences, Osaka University Faculty of Pharmaceutical Sciences, Osaka University Faculty of Pharmaceutical Sciences, Osaka University Faculty of Pharmaceutical Sciences, Osaka University
In the reaction of 2, 4 (5)-dialkylimidazoles, hydroxymethylated products (II) and dihydropyrazine derivatives (III) were obtained considerable yield in weakly acidic media, but poor yield in weakly basic media. These two reaction products (II) and (III) would be formed competitively.
