Studies on Peptides. LIV. Synthesis of the Protected Tetradecapeptide corresponding to Positions 9 through 22 of Porcine Motilin, a Gastric Motor Activity Stimulating Polypeptide

Abstract

The protected tetradecapeptide corresponding to positions 9 through 22 of porcine motilin, Z (OMe)-Glu (OBzl)-Leu-Gln-Arg (Tos)-Met-Gln-Glu (OBzl)-Lys (Z)-Glu (OBzl)-Arg-(Tos)-Asn-Lys(Z)-Gly-Gln-OH, was synthesized to serve as a starting material for the total synthesis of this gastric motor activity stimulating polypeptide.