抄録
A facile one step synthesis of hypoxanthine and 1-alkylhypoxanthines from 2-cyano-2-phenylazoacetamide and its N-alkyl analogs has been achieved by means of catalytic reduction in ammonia-formamide system at elevated temperature. Mechanistic investigation has revealed a pathway involving pyrimidine ring-closure followed by imidazole ring-closure for this reaction.
