抄録
The reaction of 1-en-3-oxo A/B trans steroid with vinylmagnesium bromide in the presence of cupric acetate afforded 1α-vinyl-3-oxo steroid. The configuration of the vinyl group introduced by the reaction was found to be α-oriented by the transformation of II into the lactone (VIII). The stereochemistry of the reduction of 1α-alkyl-3-oxo steroids and 5β-alkyl-3-oxo steroids with complex metal hydride was also studied.
