Excretion of 4-Formylaminoantipyrine as a New Metabolite of Aminopyrine in Experimental Animals

Abstract

As an extention of the studies on metabolism and excretion of aminopyrine, 4-formylaminoantipyrine which has been already reported as a new metabolite in man's urine was detected also in the urine of rabbits, guinea pigs and rats by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS).