Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Polycyclic N-Hetero Compounds. XII. Reactions of Dihydroxynaphthalenes with Formamide or Trisformylaminomethane
小山 鷹二茂在 俊光廣田 喬石野 義和大森 晋爾大和 正利
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1976 年 24 巻 11 号 p. 2585-2588

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Syntheses of tetraazatriphenylenes (II, VI, VIII) from dihydroxynaphthalenes (I, V, VII) with formamide or trisformylaminomethane (Chart 1) are described. Reaction of ethyl 1, 3-hydroxy-2-naphthoate (III) with trisformylaminomethane afforded II and N2-(1, 3-dihydroxy-2-naphthoyl) formamidine (IV). Ammonolysis of III with formamidine acetate gave IV.
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© The Pharmaceutical Society of Japan
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