Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on O-Alkylated Imides. II. Some Reactions of O-Ethyl Succinimide and O-Ethyl 4, 4-Dimethyl-glutarimide
TAKAO YAMAZAKIKATSUHIDE MATOBASUGUKI IMOTOMASANAO TERASHIMA
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1976 Volume 24 Issue 12 Pages 3011-3018

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Abstract
O-Ethyl succinimide (I) and O-ethyl 4, 4-dimethylglutarimide (II) were reacted with active methylene compounds (ethyl cyanoacetate and ethyl acetoacetate), phenylhydrazine and its derivatives, and N-bromosuccinimide. Furthermore, the salt formation of the cyanoacetylidene compound (III), the hydrolysis of the acetoacetylidene compound (VIII), the Fischer indolization of the imidrazones (XIII and XIV), and the Favorskii rearrangement of the 3-bromo-imides (XX and XXI) were examined.
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© The Pharmaceutical Society of Japan
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