Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Acid-Catalyzed Methanolysis of optically Active N-Cyclohexyl Methylphenyl-phosphinamide : A Stereochemical Evidence for A-2 Mechanism
TORU KOIZUMIYOSHIKO KOBAYASHIEIICHI YOSHII
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1976 Volume 24 Issue 4 Pages 834-835

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Abstract
A stereochemical study of the acid-catalyzed methanolysis of N-cyclohexyl methyl-phenylphosphinamide shows that the reaction proceeds by almost pure A-2 mechanism irrespective of the acidity of the reaction medium.
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© The Pharmaceutical Society of Japan
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